Advanced Electrochemical Detector for Highly Sensitive Compound Analysis

Liquid chromatography

Advanced Electrochemical Detector for Highly Sensitive Compound Analysis

26 Sep, 2023

Published over 2 years ago. See the latest and most current information on Liquid chromatography.

The electrochemical detector ED743 is a highly sensitive and highly selective detector for compounds that easily react (oxidise / reduce) electrochemically.

Highly sensitive detection for electrochemically reactive compounds (10 to 100 times more sensitive than a UV detector)

Electrodes can be chosen according to the compounds to be analysed.

  • Diamond electrode (partially compatible with glassy carbon): Phenolic compounds, vitamins, catecholamines and related substances, amino acids, and peptides.
  • Gold electrode: Sugars and alcohols.
  • Platinum electrode: Hydrogen peroxide.
  • Silver electrode: Iodine.

Highly sensitive detection of sugars (Gold electrode)

With ED743, a gold electrode can also be selected. Gold electrodes can analyse sugars with higher sensitivity than RI detectors and fluorescence detectors. The pulse potential as shown in the figure below is repeatedly applied to measure while constantly removing dirt adhering to the electrode surface.

No electrode polishing required Built-in online electrode cleaning function (Diamond electrode)

Through the use of a diamond electrode, which has a wider potential range that can be applied than common electrodes, even compounds that have high redox potential, like disulfides (for instance, oxidised glutathione and the like), can be measured.

Improved maintainability Pursuing further ease of use compared to conventional product

By applying a very high potential to the diamond electrode, the deposits on the electrode surface can be removed. Therefore, unlike the conventional working electrode, highly reproducible data can be obtained without performing complicated operations such as removing from the flow cell and polishing.

We are pleased to introduce our lineup of LC-related products. If you are interested, please do not hesitate to contact us. We will be delighted to provide them.

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