LC-MS
Facile LC-MS/MS Analysis of sphingolipids Using Metal-free Column
Jun 26 2019
In LC analyses of sphingophospholipids, such as sphingosine-1-phosphate(S1P) and ceramide-1-phosphate (C1P), a phosphate group in these molecules causes significant peak tailing, and therefore loss of sensitivity and reproducibility.
Recently, an improved LC-MS/MS method using a YMC-Triart C18 column in metal-free hardware was published by Gowda et al in the "Analytical and Bioanalytical Chemistry" journal. This application note shows the improved method using a YMC-Triart C18 metal-free column in comparison with the method using a conventional C18 column.
Digital Edition
Chromatography Today - Buyers' Guide 2022
December 2021
In This Edition Modern & Practocal Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...
View all digital editions
Events
Oct 10 2023 Hybrid event
Oct 15 2023 Katowice, Poland
Nov 05 2023 Vienna, Austria
Nov 12 2023 Louisville, KY, USA
Nov 13 2023 Plainsboro, NJ, USA
