LC-MS

  • Are Your Fillings Safe? — Chromatography Investigates

Are Your Fillings Safe? — Chromatography Investigates

Jun 25 2018 Read 746 Times

Being a child of 1960s Britain means different things to different people. Flower power, beatnik and hippies or the Vietnam War and its consequences. For me it means bad teeth and a mouth full of fillings. Then fillings were made from amalgam — a metal alloy of mercury, silver and copper that has been used for centuries to fill holes in teeth. There is no proof that the mercury in them can leach and cause other medical problems — but scare stories remain.

Composites in your mouth

More recently, composite materials are used to fix our teeth and make our smiles straight. Composites have many advantages over amalgams, particularly in that they can be made to match the colour of existing teeth, hence making them more discreet.

A dental composite is simply a coloured plastic and glass mixture that can be used in various dental applications — including as an alternative to amalgam. Because composites can be coloured to match the existing teeth, they are also used for cosmetic applications to improve smiles. But there are potentially other issues with composites used in dentistry.

Bisphenol A — ubiquitous in life

Bisphenol A, or BPA, is found in plastics that we use every day. BPA is an important monomer and is commonly used in many polycarbonate applications. From sports equipment to compact discs to dental composites — there is no getting away from BPA. Alongside its use as a monomer it also acts as an antioxidant or polymerization inhibitor.

It was in the late 1990s that concerns about BPAs effect on animals was first raised — primarily because of its ability to mimic the affects on estrogen in humans and animals. This is due to the two functional phenol groups on both BPA and estradiol. Subsequently, you now see ‘BPA free’ stickers on many of the plastic food items like water bottles that you can buy. But what about your fillings — are they BPA safe?

BPA from the dentist?

It has been reported that BPA has been found to leach from some composite dental materials — so a team from Norway set out to see whether leaching of BPA occurs immediately after treatment and two weeks later. In a report published in the journal Acta Biomaterialia Odontologica Scandinavica Presence and leaching of bisphenol a (BPA) from dental materials — they discuss how they used liquid chromatography to see what’s leaching from our fillings.

Liquid chromatography can be used for many different applications — one discussed in this article, Utilisation of LC/MSMS (QTRAP) and Polarity Switching for the Quantitative Analysis of Over 300 Pesticides in Crude QuEChERS Extracts from Various Fruit and Vegetable Matrices — involves keeping our fruit and veg safe to eat.

They found no significant differences in the amount of BPA that leached from the composites tested after 24 hours compared to those tested after two weeks. The levels they recorded were also very low and they suggest that they represent only a very small contribution to our overall BPA exposure.

Keep smiling.

Read comments0

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.


Digital Edition

Chromatography Today - September 2018

September 2018

In This Edition Articles - The Past, Present, and Future (?) of Analytical Supercritical Fluid Chromatography - a 2018 Perspective - Column Technology for Achiral SFC Separations - Practica...

View all digital editions

Events

HUPO 2018

Sep 30 2018 Orlando FL, USA

SPICA 2018

Oct 07 2018 Darmstadt, Germany

SFC 2018

Oct 17 2018 Strasbourg, France

analytica China

Oct 31 2018 Shanghai, China

View all events