See the wood in the trees! Uncover low abundance proteins and biomarkers!

Protein Depletion enables greater analysis of the proteome. Sigma offers a complete line of products optimized for the depletion of highly abundant proteins from a variety of biological samples whether you use one or two-dimensional electrophoresis, single or multidimensional chromatography or go straight to mass spectrometry.

Proteomics analysis schemes require up and downstream reagent and instrument compatibility for today’s integrated 2-dimensional electrophoresis, multi-dimensional chromatography and mass spectrometry platforms.

Complete recovery and enrichment of selective fractions permit global and targeted proteomics. Low abundance proteins and biomarkers are often masked and require unique tools to observe and compare genuinely representative data sets.

Protein Depletion enables greater analysis of the proteome. Whether you use one or two-dimensional electrophoresis, single or multidimensional chromatography or go straight to mass spectrometry. Sigma offers a complete line of products optimized for the depletion of highly abundant proteins from a variety of biological samples. Not only are a range of depletion media available for your sample of interest; human, mouse, rat or plant. But these are also provided in spin column, LC, or automated formats for your specific application.

The Sigma Life Sciences Depletion Range

Link to the entire ProteoPrep® Depletion Range

Link to the entire Seppro® Depletion Range

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