Mass spectrometry tests HDGF
HDGF tested with mass spectrometry

HPLC, UHPLC

Mass spectrometry tests HDGF

15 Apr, 2011

Published over 15 years ago. See the latest and most current information on HPLC, UHPLC.

Scientists have identified hepatoma-derived growth factor (HDGF) as a phosphoprotein using mass spectrometry.

The study, conducted by Allen Everett, Jun Yang, Monzur Rahman, Pratima Dulloor and David Brautigan, was published in the BMC Cell Biology journal.

Testing on mice, the scientists found that aortic vascular smooth muscle cells were phosphorlyated.

Following tests, they concluded that: "HDGF is a phosphoprotein and phosphorylation of S103 is mitosis related and required for its function as a mitogen."

They added that this cell cycle could also have an important part to play in "vascular cell proliferation".

BMC Cell Biology is an online open-access journal used as a resource by scientists.

Publishing peer-reviewed articles focusing on cell biology, the site is part of BioMed Central, which releases studies as soon as possible after review.

It also hosts a variety of other scientific journals - including BMC Medicine and BMC Biology - publishing content on a variety of subject areas.
 

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