HPLC, UHPLC
HPLC analyses 8-oxodG in oesophageal cancer patients
Dec 07 2010
The study was an attempt to determine how 8-oxodG levels are related to genetic susceptibility and antioxidant vitamin presence as part of an investigation into elevated oxidative stress seen in previous research.
HPLC with electrochemical detection allowed for 8-oxodG in peripheral blood mononuclear cells to be identified and analysed alongside genetic tests and vitamin measurements.
The scientists report that they were unable to prove a statistically significant connection between vitamin levels in serum, genetic polymorphisms and the 8-oxodG levels in their cancerous and control participants.
Studies disseminated in the Journal of Experimental & Clinical Cancer Research cover all aspects of oncology, with the aim of creating a high-quality discussion platform for basic, translational and clinical cancer analysis.
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