• Silica bonded phases for Polar and Non-polar Molecules

Columns (LC)

Silica bonded phases for Polar and Non-polar Molecules

May 14 2013

The Cogent TYPE-C™ silica bonded phases, manufactured by MicroSolv Technology Corporation (USA), have a surface populated by silicon-hydride functional groups instead of silanols. Patented bonding technology is then used to produce the Cogent Bidentate C18, Bidentate C8, UDC-Cholesterol, Phenyl and Diamond Hydride (the “Metabolomics Column”) phases, with direct silicon-carbon bonds on the silica hydride surface. These bonded phases have the ability to retain polar solutes at high concentrations of organic solvent by aqueous normal-phase (ANP). In addition, non-polar compounds can also be retained on the same column under reversed-phase conditions. The lack of surface silanols leads to fast equilibration times, excellent peak shape and extended column lifetimes for the assay of a wide range of pharmaceuticals, organic acids, carbohydrates, biochemicals, peptides, metabolites and many other compounds. For further information and a technical brochure on Cogent TYPE-C silica HPLC columns, email Hichrom Limited at: technical@hichrom.co.uk or Tel: 0118 930 3660 or www.microsolvtech.com


Digital Edition

Chromatography Today - Buyers' Guide 2022

December 2021

In This Edition Modern & Practocal Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...

View all digital editions

Events

ASMS Conference

Jun 04 2023 Houston, TX, USA

Plastics Recycling World Expo Europe

Jun 14 2023 Essen, Germany

HPLC 2023

Jun 18 2023 Dusseldorf, Germany

SinS

Jul 04 2023 Cardiff, UK

Water Expo Nigeria 2023

Jul 11 2023 Lagos, Nigeria

View all events