• All New HIC Column for High Throughput Analyses: BioPro HIC HT

Bioanalytical

All New HIC Column for High Throughput Analyses: BioPro HIC HT

Mar 24 2020

YMC’s latest hydrophobic interaction chromatography column, BioPro HIC HT, is especially designed for biopharmaceuticals such as antibody-drug-conjugates (ADCs). Higher flow rates can be applied due to an extremely high-pressure stability, which allows very short run times and high sample throughput.

BioPro HIC HT columns are the ideal choice for drug-to-antibody ratio (DAR) determination due to a novel and optimised surface chemistry. Higher resolution is offered compared to conventional HIC columns as its surface modification suppresses excessive or strong absorption of ACDs and result in highly reliable quantifications.

The rigid 2.3 µm non-porous polymer particles with butyl modification are pressure tolerant up to 400 bar and allow rapid analyses by increased flow rates without loss of resolution. Such fast runs are not possible with other HIC columns due to their much lower pressure limit, which is usually only the half that of BioPro HIC HT.

BioPro HIC HT is the perfect solution for quality control applications not only due to the possibility of high throughput runs, but also the excellent batch-to-batch reproducibility provided by YMC.

The reproducibility together with the high column stability ensures highest reliability for your separations!


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