Fast and easy method development for large scale processes
Jan 25 2022
Before implementing large scale processes, the most straightforward approach is to develop and refine separation methods on a laboratory scale. Only then, risks and resource consumption can be kept on a bare-minimum. Also, it allows fast process modifications.
Self-packed glass columns are “the” lab tool for quick screenings due to two reasons:
- any stationary phase available already in the lab can be chosen and
- the packing is fast so that results are quickly obtained.
ECOPLUS columns as the perfect tool in method development
The approach has been successfully used in a recent study by Stefan Schmidt et al. They developed a brand-new method to purify mAb in large-scale production. Their approach was based on self-packed ECOPLUS glass columns.
The advantages are:
- Low sample, resin and solvent consumption
- High reproducibility
- Easy column packing
- Full biocompatibility for BioLC applications
You want to read more? Check out our Technical Note.
Chromatography Today - Buyers' Guide 2022
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