Fast and easy method development for large scale processes

Bioanalytical

Fast and easy method development for large scale processes

25 Jan, 2022

Published over 4 years ago. See the latest and most current information on Bioanalytical.

Before implementing large scale processes, the most straightforward approach is to develop and refine separation methods on a laboratory scale. Only then, risks and resource consumption can be kept on a bare-minimum. Also, it allows fast process modifications.

Self-packed glass columns are “the” lab tool for quick screenings due to two reasons:

  • any stationary phase available already in the lab can be chosen and
  • the packing is fast so that results are quickly obtained.

ECOPLUS columns as the perfect tool in method development

The approach has been successfully used in a recent study by Stefan Schmidt et al. They developed a brand-new method to purify mAb in large-scale production. Their approach was based on self-packed ECOPLUS glass columns.

The advantages are:

  • Low sample, resin and solvent consumption
  • High reproducibility
  • Easy column packing
  • Full biocompatibility for BioLC applications

You want to read more? Check out our Technical Note.

Explore Our Other Sites

Labmate Online
Novel CAR T cell therapy shows strong early promise to 'eliminate' glioblastoma
Explore more Arrow
Envirotech Online
EU ETS benchmark update puts industrial emissions data under sharper scrutiny
Explore more Arrow
Pollution Solutions Online
Next-generation reverse osmosis membranes for more efficient and cost-effective seawater desalination
Explore more Arrow
Petro Online
New test method ASTM D8606 has been officially released
Explore more Arrow