Fast and easy method development for large scale processes
Jan 25 2022
Before implementing large scale processes, the most straightforward approach is to develop and refine separation methods on a laboratory scale. Only then, risks and resource consumption can be kept on a bare-minimum. Also, it allows fast process modifications.
Self-packed glass columns are “the” lab tool for quick screenings due to two reasons:
- any stationary phase available already in the lab can be chosen and
- the packing is fast so that results are quickly obtained.
ECOPLUS columns as the perfect tool in method development
The approach has been successfully used in a recent study by Stefan Schmidt et al. They developed a brand-new method to purify mAb in large-scale production. Their approach was based on self-packed ECOPLUS glass columns.
The advantages are:
- Low sample, resin and solvent consumption
- High reproducibility
- Easy column packing
- Full biocompatibility for BioLC applications
You want to read more? Check out our Technical Note.
In This Edition Modern & Practocal Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...
View all digital editions
Dec 04 2022 Cancun, Mexico
Feb 01 2023 Amsterdam, Netherlands
Feb 06 2023 Dubai, UAE
Feb 26 2023 Darmstadt, Germany
Mar 01 2023 Shanghai, China