Bioanalytical
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Before implementing large scale processes, the most straightforward approach is to develop and refine separation methods on a laboratory scale. Only then, risks and resource consumption can be kept on a bare-minimum. Also, it allows fast process modifications.
Self-packed glass columns are “the” lab tool for quick screenings due to two reasons:
The approach has been successfully used in a recent study by Stefan Schmidt et al. They developed a brand-new method to purify mAb in large-scale production. Their approach was based on self-packed ECOPLUS glass columns.
The advantages are:
You want to read more? Check out our Technical Note.