• The vaccine is already in use in areas of the world for the treatment of TB

TB vaccine could 'cure' MS

Dec 05 2013 Comments 0

A tuberculosis vaccine that is used in some areas of the world could be used to prevent the progression of multiple sclerosis (MS). A new study has suggested that the vaccine could help to avoid the progression of the disease when given to those that are showing early signs of it. The study, published in the journal 'Neurology', shows that a medication that is already in use could help reduce the number of patients that develop MS.

MS is an incredibly difficult disease to diagnose and some doctors will attempt to rule out any other illness before finally diagnosing it, which can allow it to progress further. The most-often reported early symptoms are balance and vision problems, along with feelings of numbness. While Magnetic Resonance Imaging (MRI) can be used to diagnose MS, many doctors will wait for other symptoms to appear before recommending a scan.

According to researchers from the Sapienza University of Rome, 50 per cent of patients that present with these early symptoms are likely to develop MS within a period of two years. Only ten per cent of patients will not develop any other MS-related symptoms.

The study followed 73 individuals who had experienced one episode of symptoms related to MS. Of these participants, 33 participants were treated with an injection of Bacille Calmette-Guerin (BCG), while the rest were given a placebo. Each of the participants underwent a brain scan every month for a period of six months before going on to be treated with interferon beta-1a - a drug for the treatment of MS - for 12 months. If any further treatment was required, it was recommended by the participant's neurologist.

After following each of the individuals for five years, it was found that those who had been treated with BCG presented with fewer brain lesions, which are a characteristic of MS, when compared to the placebo group. On average, those treated with the vaccine had three lesions, while the average number amongst the placebo group was seven.

Of those who received a placebo, 70 per cent went on to develop MS, while only 43 per cent of the vaccinated group developed the disease. 

Although none of the individuals that received BCG experienced any adverse effects, the researchers have said more work needs to be done until the vaccine can be treated as a cure for MS.

Read comments0

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Digital Edition

Chromatography Today - November / December 2017 Volume 10 Issue 4

December 2017

In this issue... Contents - Foreword by Trevor Hopkins Articles - The Emergence of Multiple Attribute Methodology (MAM) Workflows - Stationary Phase Selection for Achiral Separation ...

View all digital editions



Jan 24 2018 Cardiff, UK


Feb 05 2018 Dubai, UAE


Mar 18 2018 Dubai, UAE


Mar 18 2018 New Orleans, LA, USA

China Lab 2018

Mar 27 2018 Guangzhou, China

View all events