• Collaboration to Increase Production of COVID-19 Treatment Announced

Purification

Collaboration to Increase Production of COVID-19 Treatment Announced

Mar 05 2021

RotaChrom Technologies, the developer of the world's first industrial-scale Centrifugal Partition Chromatography (CPC) technology platform, announces the launch of a collaboration with Cyclolab Cyclodextrin Research and Development Laboratory Ltd, a cyclodextrin research, development and manufacturing company. This strategic partnership between Cyclolab and RotaChrom aims to develop a more efficient and cost-effective process to purify Remdesivir, which is a widely used treatment option for COVID-19.

The partnership will combine RotaChrom’s scalable CPC technology with Cyclolab’s knowledge and experience with cyclodextrins. The scalable system that will be utilised for this collaboration includes RotaChrom’s pilot-scale centrifugal partition chromatographic, known as the rCPC, that utilises an innovative methodology of chromatography where separation occurs between two immiscible liquid phases, offering several advantages compared to more traditional methods. The result is a more purified compound of interest at a lower cost due to increased efficiency and automation.

“While the world anxiously waits for COVID-19 vaccines to be distributed, many are already infected and suffering from this terrible virus,” said RotaChrom CEO László Madarász. “By enhancing the production of a proven drug that has the ability to treat those who are already sick, we could potentially improve lives. We are proud to provide a solution by combining our company’s technologies with Cyclolab to create this much-needed strategic partnership.”

Cyclolab is a company with unparalleled expertise in the manufacturing, design and formulation of cyclodextrins. For this new collaboration, Cyclolab will provide its cyclodextrin-related analytical, formulation and chemistry expertise that spans back to the 1970s. In the three-staged collaboration that kicked off in early 2021, Cyclolab and RotaChrom aim to explore the potential synergies of the companies’ technologies and evaluate how a more economic purification alternative could be discovered.

“Cyclolab is a pioneer and a global leader in cyclodextrin science, and we are delighted to be working with RotaChrom, a unique company with state-of-the-art chromatography capabilities,” said Tamás Sohajda, CEO of Cyclolab.

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