New LC-MS/MS delivers increased productivity and sensitivity performance

HPLC, UHPLC

New LC-MS/MS delivers increased productivity and sensitivity performance

16 Jul, 2012

Published over 13 years ago. See the latest and most current information on HPLC, UHPLC.

Shimadzu UK Ltd is launching what is claimed to be the world’s fastest LC-MS/MS, the LCMS-8040, which offers users increased levels of productivity as it enables laboratories to run more scans and collect more data from fewer sample injections. An expansion of Shimadzu’s ultrafast mass spectrometry (UFMS) series, the instrument also features high sensitivity capabilities which deliver accurate measurements at low levels and high speeds so users can be confident in the results.

The robust LCMS-8040 features the fastest quadrupole scan speed of 15,000 u/sec at 0.1 Da step size, as well as the world's fastest polarity switching at 15 msec. The instrument is capable of ultrafast MRM transition monitoring, up to a maximum 555 MRMs per second. Plus, the LCMS-8040’s patented power supply technology allows the shortest loop time to give both positive and negative ion data in the shortest time.

The ability to scan faster, in addition to the world’s shortest pause and dwell times, of 1 and 0.8 msec respectively, means that the LCMS-8040 is able to create more points across a peak resulting in better quantitation to deliver more accurate measurements, first time. The result is more information with less work which leads to improved productivity as well as an increased level of confidence in the results. For users doing method development, the LCMS-8040 enables full scan data and MRM to be captured simultaneously which allows the matrix effects to be seen more clearly.

The new LCMS-8040 features re-engineered ion optics and collision cell technology that results in higher ion transmission and collision induced dissociation efficiency which translates into major sensitivity performance benefits.

The new instrument, which can be upgraded from Shimadzu’s LCMS-8030, is ideal for a wide variety of laboratory applications including clinical analysis, drugs of abuse screening, ADME analysis, environmental analysis and food testing. Shimadzu is also offering customers a discount on the LCMS-8040 in return for trading in old ABSciex, Waters and Thermo Scientific Triple Quadrupole models.

For more information www.shimadzu.co.uk

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