Size exclusion, gel permeation chromatography (GPC)
Advanced polymer analysis reveals structural differences beyond molecular weight
Apr 10 2025
A major European producer of high-performance water-soluble polymers has adopted Testa Analytical’s COMBO-ONE detector to gain deeper insights into the structural characteristics of their materials. Integrated into a GPC/SEC system, the detector enables precise analysis of polymers that share similar molecular weights but exhibit differing functional properties.
Despite comparable molecular weight and distribution, the polymers under investigation demonstrated structural differences that influence their performance in application-specific environments.
Testa Analytical’s applications specialist, Hizkia Chandra, noted:
“On the very first day of installation, the Combo ONE detector uncovered critical structural differences between samples. Paired with a high-end Shimadzu GPC/SEC system, the results were both immediate and highly valuable.”
The COMBO-ONE combines a differential refractometer and viscometer into a compact, integrated unit that eliminates the need for delay volume correction. This streamlined approach improves accuracy in characterising key polymer parameters - particularly those that relate to structure - offering manufacturers a powerful tool for material development and quality control.
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