Size exclusion, gel permeation chromatography (GPC)
Testa Analytical reports that its Differential Refractometer improves the precision of dn/dc determination using light scattering techniques. An accurate dn/dc value is essential in molecular weight determination of biopolymers and polymers by light scattering.
Backed by decades of experience of Gel Permeation Chromatography (GPC) and Light Scattering techniques, Testa Analytical has created a differential refractometer accessory for light scattering instruments that deliver exceptional performance and is easy-to-use.
The Differential Refractometer is a flexible device which allows fast determination of the specific refractive index increment (dn/dc) of dissolved samples with extremely high accuracy and in just a few minutes. Without any limitations in terms of solvent and with a wide range of measurement temperatures, it is a true workhorse and a valuable addition to any Light Scattering lab. Beneficially, the system also offers different wavelength options enabling precise matching of your light scattering instrument laser operating wavelength, thereby ensuring reliable and reproducible results every time.
The Differential Refractometer operates via a PC using intuitive Windows™ based software which additionally offers the possibility to determine the accurate Concentration of samples with known dn/dc.
The unique design of the instrument furthermore allows total recovery of the measured samples without any dilution or pollution. Samples used for dn/dc can then directly be used for Light Scattering, reducing therefore the time needed for sample preparation and avoiding errors.
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