HPLC, UHPLC
Scientists isolate novel active peptides from soy protein
May 24 2011
In a study published by Lipids in Health and Disease, a team of scientists investigated the effects of soy protein-derived peptides on lipid metabolism - paying particular attention to triglyceride (TG) metabolism - in HepG2 cells and obese Otsuka Long-Evans Tokushima fatty (OLETF) rats.
The team undertook five separate experiments, the first two of which revealed that soy crude peptide (SCP)-LD3 showed hypolipidemic effects in HepG2 cells and OLETF rats and hydrophilic fraction, separated from SCP-LD3 with hydrophobic synthetic absorbent, revealed lipid-lowering effects.
Then, through a process involving gel permeation chromatography-high performance liquid chromatography, the team revealed that Fraction-C (Frc-C) peptides significantly reduced TG synthesis and apolipoprotein B (apoB) secretionin HepG2 cells.
As a result of all of the experiments, the scientists managed to isolate the novel active peptides with TG-lowering effects from soy protein.
Digital Edition
Chromatography Today - Buyers' Guide 2022
October 2023
In This Edition Modern & Practical Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...
View all digital editions
Events
May 05 2024 Seville, Spain
May 15 2024 Birmingham, UK
May 19 2024 Brno, Czech Republic
May 21 2024 Lagos, Nigeria
May 23 2024 Beijing, China