HPLC used in vitamin deficiency study
HIV infection found to have an impact on vitamin A levels.

HPLC, UHPLC

HPLC used in vitamin deficiency study

18 Jul, 2011

Published over 14 years ago. See the latest and most current information on HPLC, UHPLC.

Scientists used high performance liquid chromatography (HPLC) in a study into vitamin A deficiency (VAD) in women of reproductive age in South East Asia and Africa.

VAD has been highlighted as a major health problem in the area but no research presently exist which determine the effect HIV infection may have on the vitamin A levels of pregnant women.

The study, published by BMC Public Health, took blood samples from 423 pregnant women and from 55 healthy volunteers and used HPLC to determine vitamin A levels.

Scientists found that, after controlling for demographic variables, VAD is lower in pregnant women without HIV infection.

The results were similar among those who were not carrying a child - almost half of non-pregnant women with HIV infection had VAD, while only 28 per cent controls were deficient for vitamin A.

As a result of the study, the scientists said that considering the implications of VAD in pregnancy, supplements should be provided to all expectant mothers.

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