HPLC looks into diabetic cardiomyopathy in mice
Sep 13 2010
Published in Cardiovascular Diabetology (CVD), the study recounts the use of HPLC to measure homocysteine levels in test subjects, with HHcy assessed as a result of this.
In order to undertake HPLC, the scientists withdrew blood from the dorsal aorta of the mice involved in their research.
This was centrifuged at four degrees C for ten minutes at 5,000 rpm to separate the clear plasma, which was then stored at -80 degrees C before being analysed.
According to the researchers, homocysteine which developed within the mice worsened their diabetic cardiomyopathy, with diastolic dysfunction - a stiffness of the ventricles of the heart - seen to occur as a result.
CVD is an open-access, peer-reviewed journal which offers insight into research advances in the study of interactions between diabetes and the cardiovascular system.
In This Edition Modern & Practocal Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...
View all digital editions
Feb 26 2023 Darmstadt, Germany
Mar 01 2023 Shanghai, China
Mar 09 2023 Guangzhou, China
Mar 18 2023 Philadelphia, PA, USA
Mar 26 2023 Indianapolis, IN, USA