HPLC, UHPLC
Gene relationships studied with LC-MS
Aug 19 2010
The team used LC-MS to look into how metabolites produced in plants are expressed differently if genes are knocked out.
Some genes have duplicates, while others do not, with the former harder to study as their activity can be reproduced elsewhere in the plant's genetic code.
However, the researchers found that functional compensation occurs at significant levels only when genes are very closely matched with their duplicates.
Studies were based on the model plant Arabidopsis thaliana and assessed the expression of 35 metabolites.
From 1,976 genes, 17 primary and 18 secondary metabolites were analysed in order to compile the results of the research.
RIKEN was founded as a private research foundation in 1917 and became a public corporation in 1958, before converting to an independent administrative institution in 2003.
Digital Edition
Chromatography Today - Buyers' Guide 2022
October 2023
In This Edition Modern & Practical Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...
View all digital editions
Events
Apr 23 2024 Kintex, South Korea
Apr 23 2024 Seoul, South Korea
Apr 28 2024 Montreal, Quebec, Canada
May 05 2024 Seville, Spain
May 15 2024 Birmingham, UK