Preparative

  • Biochemistry of prostate health studied with column chromatography
    The biochemistry of prostate health has been investigated with column chromatography

Biochemistry of prostate health studied with column chromatography

Jan 19 2011 Read 1153 Times

Column chromatography has been used by a team of researchers to look into the biochemistry processes behind prostate health.

The scientists, from Brigham Young University, Children's Hospital Boston and Harvard Medical School and Stoelting Co, reveal their findings in a research report in Reproductive Biology and Endocrinology (RB&E).

Column chromatography was used to analyse steroids incubated with equol as part of in vitro investigation into the biochemistry processes governing equol's impact on prostate health.

They found maximum and half-maximal binding between equol and 5alpha-dihydrotestosterone occurred with 100 nM and 4.8 nM of equol respectively.

As a result, prostate weight in rat test subjects decreased, but testosterone, estradiol and luteinising hormone levels were unaffected.

The researchers conclude that administration of equol could help in maintaining prostate health and with combating disorders associated with 5alpha-dihydrotestosterone mediation.

RB&E aims to provide information about the latest research developments to endocrinologists working within the industry.ADNFCR-3194-ID-800351032-ADNFCR
Read comments0

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.


Digital Edition

Chromatography Today - September 2018

September 2018

In This Edition Articles - The Past, Present, and Future (?) of Analytical Supercritical Fluid Chromatography - a 2018 Perspective - Column Technology for Achiral SFC Separations - Practica...

View all digital editions

Events

HUPO 2018

Sep 30 2018 Orlando FL, USA

SPICA 2018

Oct 07 2018 Darmstadt, Germany

SFC 2018

Oct 17 2018 Strasbourg, France

analytica China

Oct 31 2018 Shanghai, China

View all events