Quantitative analysis shows impact of smoking on DNA
Quantitative analysis suggests DNA in smokers is twice as damaged as in non-smokers

Electrophoretic separations

Quantitative analysis shows impact of smoking on DNA

18 Nov, 2010

Published over 15 years ago. See the latest and most current information on Electrophoretic separations.

Electrophoresis has allowed scientists to complete quantitative analysis of the damage caused to DNA by smoking.

A team from the University of Basel looked at the effects of smoking half a pack of cigarettes on a daily basis.

Their findings, published in Tobacco Induced Diseases, discuss how electrophoresis allows these effects to be measured through quantitative analysis of the damage caused.

"DNA breaks lead to smaller pieces of DNA, which migrate out of the nucleus forming a tail during gel electrophoresis," they explain.

In their study, smokers exhibited more than double the level of damage seen in non-smokers on both assessment criteria, olive moment and tail moment.

According to the scientists, oxidative stress caused by smoking could be one mechanism by which these breaks in DNA occur.

Tobacco Induced Diseases is concerned with the underlying mechanisms behind the creation of tobacco-induced diseases, along with ways in which addiction might be prevented.

Latest News

Explore Our Other Sites

Labmate Online
Mayo Clinic and Thermo Fisher Scientific launch Precure LLC to identify signs of disease before their symptoms appear
Explore more Arrow
Envirotech Online
Connected safety technology company announces CEO appointment and leadership transition
Explore more Arrow
Pollution Solutions Online
Smarter wastewater management helps futureproof distillery operations and protect local watercourses
Explore more Arrow
Petro Online
Improving repeatability in diesel fuel lubricity testing
Explore more Arrow