• Practical Guidelines for Capillary Anion-Exchange Chromatography

Preparative

Practical Guidelines for Capillary Anion-Exchange Chromatography

Thermo Fisher Scientific is pleased to announce a technical note describing procedures and practices that help chromatographers get the most out of their capillary ion-chromatography system. Technical Note 113: Practical Guidance for Using Capillary Anion Chromatography presents tips and techniques that will help ensure that good chromatographic results are obtained as system volumes are reduced for capillary IC.
Capillary ion chromatography (IC), which separates ions using 0.4 mm diameter columns at 10–30 μL/min flow rates, provides increased mass sensitivity, reduces water consumption, and reduces waste generation to only ~5 L per year. The increased mass sensitivity is ideal for samples of limited amount and for trace analysis. To achieve these benefits, some additional care is required to maintain flat ends on tubing, to prevent gaps between tubing and connectors, and to prevent air bubbles from being trapped in the capillary system. TN 113 describes techniques for plumbing and flushing the system, and procedures for performing trace analyses, including direct large loop injections and concentrator column installation and loading.
This technical note and many others can be found at www.thermoscientific.com/dionex under the Documents tab. 


Events

ASMS Conference

Jun 01 2025 Baltimore, MD, USA

HPLC 2025

Jun 15 2025 Bruges, Belgium

LabAsia 2025

Jul 14 2025 Kuala Lumpur, Malaylsia

SinS Solutions in Science

Jul 15 2025 Brighton, UK

ACS National Meeting - Fall 2025

Aug 17 2025 Washington DC, USA & Virtual

View all events