Sample Preparation for Drug testing via Hair Analysis
Aug 07 2019 Read 375 Times
It is dissolved in certain acids and then analysed via gas chromatography or the mass spectrometer. The dissolving in the acid is accelerated and improved through the enhancement of the specific surface area of the sample. Here the Fritsch Mini-Mill -PULVERISETTE 23 is used.
In a 15ml steel cup, 300-500mg hair is weighed. As a grinding body a 15mm steel ball is used. After a grinding duration of 5 minutes a fine powder is attained (< 100µm), which can be used for the following analysis.
For larger amounts or for the grinding of two samples simultaneously, the Fritsch Planetary Micro Mill PULVERISETTE 7 classic line can be used. In a 45 ml grinding bowl made of zirconium oxide, sintered corundum, silicon nitride approximately 0.1-1g of hair is weighed in and 7x15mm grinding balls are added. The grinding time is 5 - 20 minutes. Afterwards a fine powder is obtained (< 100 µm), which can be used for additional analysis.
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