Sample Preparation for Drug testing via Hair Analysis
Aug 07 2019 Read 375 Times
It is dissolved in certain acids and then analysed via gas chromatography or the mass spectrometer. The dissolving in the acid is accelerated and improved through the enhancement of the specific surface area of the sample. Here the Fritsch Mini-Mill -PULVERISETTE 23 is used.
In a 15ml steel cup, 300-500mg hair is weighed. As a grinding body a 15mm steel ball is used. After a grinding duration of 5 minutes a fine powder is attained (< 100µm), which can be used for the following analysis.
For larger amounts or for the grinding of two samples simultaneously, the Fritsch Planetary Micro Mill PULVERISETTE 7 classic line can be used. In a 45 ml grinding bowl made of zirconium oxide, sintered corundum, silicon nitride approximately 0.1-1g of hair is weighed in and 7x15mm grinding balls are added. The grinding time is 5 - 20 minutes. Afterwards a fine powder is obtained (< 100 µm), which can be used for additional analysis.
Digital Edition
Chromatography Today - September 2019
September 2019
In This Edition Fundamental ASpects The Quest for True Ultra High Performance Supercritical Fluid Chromatography Walk-up SFC-MS for Fast Purification of reaction Mixtures within Discover...
View all digital editions
Events
Sep 24 2019 Sao Paulo, Brazil
Sep 29 2019 Bethesda, MD, USA
Sep 30 2019 Philadephia, PA, USA
Oct 27 2019 Basel, Switzerland
Nov 18 2019 Princeton, NJ, USA
Reader comments
Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.