• Sample Preparation for Drug testing via Hair Analysis

Preparative

Sample Preparation for Drug testing via Hair Analysis

Aug 07 2019

In order to prove the consumption of drugs (cocaine, cannabis products, amphetamines) even after long periods of time, hair is frequently analysed.

It is dissolved in certain acids and then analysed via gas chromatography or the mass spectrometer. The dissolving in the acid is accelerated and improved through the enhancement of the specific surface area of the sample. Here the Fritsch Mini-Mill -PULVERISETTE 23 is used.

 

In a 15ml steel cup, 300-500mg hair is weighed. As a grinding body a 15mm steel ball is used. After a grinding duration of 5 minutes a fine powder is attained (< 100µm), which can be used for the following analysis.

For larger amounts or for the grinding of two samples simultaneously, the Fritsch Planetary Micro Mill PULVERISETTE 7 classic line can be used. In a 45 ml grinding bowl made of zirconium oxide, sintered corundum, silicon nitride approximately 0.1-1g of hair is weighed in and 7x15mm grinding balls are added. The grinding time is 5 - 20 minutes. Afterwards a fine powder is obtained (< 100 µm), which can be used for additional analysis.

More information online: www.fritsch.de


Digital Edition

Chromatography Today - Buyers' Guide 2022

December 2021

In This Edition Modern & Practocal Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...

View all digital editions

Events

PITTCON 2022 - POSTPONED TO 2023

Mar 05 2022 Atlanta, GA, USA

Israchem

Mar 08 2022 Tel Aviv, Israel

ACS National Meeting & Expo, Spring 2022

Mar 20 2022 San Diego, CA, USA & Virtual

China Lab 2022

Mar 31 2022 Guangzhou, China

MSB 2022

Apr 03 2022 Liege, Belgiulm

View all events