In this issue:
SAMPLE PREPARATIONS

Matrix Effects and Matrix Affects: The Impact of Different Sample Matrices on Sample Preparation and Chromatographic Analysis

Biopharmaceutical Peptide Mapping; Addressing the Challenges with Simple Fast, and Reproducible Workflows

Biocompatible Solid Phase Microextraction (BioSPME) of Drugs of Abuse from Urine

An Investigation into the Effect of Chemical and Physical Polymer Structure on Reverse Phase Extraction of Small Molecules such as Paracetamol and Haloacetic Acids

LARGE MOLECULE SEPARATION AND PURIFICATION

Method Development for Reproducible Flash Purification of Pharmaceuticals by UHPLC and HPLC

Why Isolate Lipids from Biological Samples? Making Lipidomics by Mass Spectrometry the Standard

High-performance Anion Exchange Chromatography coupled with Pulsed Amperometric Detection (HPAE-PAD) – An Effective Tool for Analysing Monosaccharides and Sialic Acids in Biosimilars

The use of High Performance Liquid Chromatography (HPLC) Columns in Biomolecule Analysis

Effects of Secondary Interactions in Size Exclusion Chromatography