VISUALISATION OF EXOCYTOSIS OF INSULIN-CONTAINING SECRETORY VESICLES IN PANCREATIC ß-CELLS USING TIRFM

Microscopy & microtechniques

VISUALISATION OF EXOCYTOSIS OF INSULIN-CONTAINING SECRETORY VESICLES IN PANCREATIC ß-CELLS USING TIRFM

12 Jun, 2008

Published over 17 years ago. See the latest and most current information on Microscopy & microtechniques.

Mr. Michael B Hoppa, Dr. Patrik Rorsman
1 min read
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One of life science's primary challenges is to understand and define the role of a number of proteins in cellular processes associated with health and disease of living organisms. Understanding this vast array of diverse biochemical processes of the living cell is paramount to not only gaining an insight into the living organism as a whole, but also discovering when and why these cellular processes break down, thus causing disease. Whilst innovative and specialised techniques have been instrumental for many advances in molecular biology, many questions concerning the structure and function of cells can only be answered by observing living cells. Live-cell imaging offers the power of capturing the dynamics of biological action in live cells and in real-time, something not previously available with biochemical approaches.

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