Columns (LC)

  • Fused-Core® Columns for High Performance Protein Separations

Fused-Core® Columns for High Performance Protein Separations

May 11 2018 Read 851 Times

As the first manufacturer of the 1,000 Å Fused-Core® particle, Advanced Materials Technology recognises the benefits of unrestricted pore access when analysing large proteins. HALO® BioClass Protein phases have been developed in both 400 Å and 1,000 Å to make the separation of large molecules by reversed-phase chromatography easier and more efficient.

HALO® Protein columns are available with C4 or new sterically-protected ES-C18 chemistries in both 2.7 µm and 3.4 µm particle sizes. Perfect for the separation of large biomolecules ≤ 500 kDa including monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs), and biosimilars, HALO® Fused-Core® columns produce narrow peaks are higher recoveries versus smaller-pore phases and fully-porous molecules. Additionally, HALO® 2.7 µm columns offer comparable peak capacities to sub-2 µm fully-porous columns at 40–50% of the backpressure.

HALO® Protein columns are manufactured to the highest quality standards, ensuring rugged column performance at low pH and high temperatures. HALO® columns are compatible with both HPLC and UHPLC instrumentation for rapid, high efficiency bioseparations.

For further details on HALO® Protein columns, information on any other HALO® product, or to discuss how to convert your HPLC method to an ultra-fast method using superficially-porous phases, contact Hichrom’s friendly and knowledgeable technical team at technical@hichrom.co.uk and they will be happy to help.

Reader comments

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Post a Comment




Digital Edition

Chromatography Today - June 2019

June 2019

In This Edition Fundamental Aspects - High-resolution MS coupled to Photoionisation - Why do you Need to Measure BTEX in Ambient Air? - Gas Chromatography - Vacuum Ultraviolet Spectroscopy...

View all digital editions

Events

ACS National Meeting & Expo, Fall 2019

Aug 25 2019 San Diego, CA, USA

Microscopy Conference 2019

Sep 01 2019 Berlin, Germany

BMSS Annual Meeting

Sep 03 2019 Manchester, UK

ICMGP 2019

Sep 08 2019 Krakow, Poland

View all events