ACQUITY UPC2  System

The ultimate solution for making the complex.....routine.

UPC²: Expanding the boundaries of LC and GC separations.

UltraPerformance Convergence Chromatography™ (UPC²™) is a new category of separations science that makes the complex analysis...routine. This new technology marries the unrealized potential of SFC with Waters proven UPLC® technology and expertise in the management of fluids, temperature, and pressure. By varying mobile phase strength, pressure, temperature, and stationary phase with UPC², one can separate, detect and quantify structural analogs, isomers, enantiomeric and diasteriomeric mixtures – all compounds or samples that challenge today’s laboratories. Because CO² is the primary mobile phase for UPC², the technique greatly reduces the use of toxic solvents.

ACQUITY UPC² System: Discover what's been missing from your analytical toolbox

With the ACQUITY UPC² System, scientists can now separate, analyze, and understand compounds that have challenged all other LC and GC technologies including:

• Hydrophobic and chiral compounds
• Lipids
• Thermally-labile samples
• Polymers

It's also the perfect complement to MS due to its low solvent load and high resolution, narrow peaks and fast separations.

System features:

• Compressed carbon dioxide (CO²), the primary mobile phase, is less costly and less toxic than liquid mobile phases or carrier gases.
• Variable volume injection delivers 0.5 µL to 10 µL as well as the ability to match column and injection volume with minimal sample loss and need to change loops.
• Higher throughput and productivity allows you to analyze more samples per day with faster re-equilibration of columns and shorter cycle times, increasing laboratory productivity.
• Co-solvent and column switching provides flexibility in method development for faster solvent screening and faster column screening.

See what ACQUITY UPC² can do for your laboratory:

Product brochure

Application Notes

Product Pricing

For more information and to speak to a Waters representative, please contact 0208 238 6100 or email uk@waters.com