• Biologically active substances 'differ in hepatitis E patients'
    Hepatitis E patients may have different biologically active substances present in their blood plasma


Biologically active substances 'differ in hepatitis E patients'

Feb 07 2011

Hepatitis E patients have been studied to determine how the biologically active substances found in their blood plasma differ from healthy individuals.

A team writing in Proteome Science explain how they used mass spectrometry to enrich the peptidome fraction of subjects' plasma.

They were able to identify a number of biologically active substances associated with immune response that were differentially expressed between the infected and control groups.

In turn, they have created a peptide profile they say could be useful in future diagnoses of hepatitis E.

The condition occurs when contaminated drinking water is consumed, according to guidance from the World Health Organization.

However, it is not known to commonly be caused by person-to-person contact, during sex or during blood transfusions.

Moreover, the condition is self-limiting and typically clears up, except in acute cases where fulminant hepatic failure may occur and no known course of treatment exists to alter the outcome.

Digital Edition

Chromatography Today - Buyers' Guide 2022

December 2021

In This Edition Modern & Practocal Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...

View all digital editions


Lab Asia 2023

Oct 10 2023 Hybrid event

MicroTAS 2023

Oct 15 2023 Katowice, Poland

ISPPP 2023

Nov 05 2023 Vienna, Austria

SETAC North America

Nov 12 2023 Louisville, KY, USA

Eastern Analytical Symposium

Nov 13 2023 Plainsboro, NJ, USA

View all events