• What Can I Expect at HPLC 2016?

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What Can I Expect at HPLC 2016?

Apr 15 2016

Chromatography is one of the key tools in a chemist’s or biochemist’s toolkit. From the mid-nineteenth century until the present day it has developed into a powerful technique that has uses as both a precursor for other techniques —such as mass spectrometry — or as a primary analytical tool in its own right.

Chromatography is the main separation technique used in laboratories, and as technology and scientific knowhow progresses, chromatography users and vendors search out new developments, techniques and solutions to the problems of today — and the future.

Chromatography fest

The next major chance for vendors and users to get together and share ideas will be in June 2016 in San Francisco at HPLC 2016. Let’s take a quick look at some of the ideas that will be shared at one of the main showcases for chromatography.

The conference covers most aspects of high performance liquid chromatography (HPLC). Liquid chromatography is probably at the forefront of biochemical research as companies search for the latest drugs — but it is also a prized technique in many other fields as noted by the HPLC 2016 symposium. Sessions on applications as varied as biofuels, polymer analysis and nutrition demonstrate HPLC’s versatility.

As well as applications, HPLC 2016 is also an opportunity scientists and technicians to find out about the latest technological developments. As always with chromatography — better separations are the goal of users everywhere. In many instances this involves smaller column particles.

It could be argued that chromatography is at its most powerful when it is used to supply samples to a mass spectrometry system. LC-MS is a powerful technique in bioanalysis of proteins and peptides. And as we search for unknown compounds, LC systems become increasingly reliant on MS as a detection system. Developments in the interface between LC and MS occupy a significant part of the symposium schedule.

Proteomics and antibody drug conjugates

Proteomics — the study of proteins, including their interactions and function — is an ever growing field in biochemistry and will be covered by both tutorials and workshops at HPLC 2016. Mapping the proteins in our cells could be the key to understanding more about ourselves and what happens when something goes wrong. LC-MS-MS (tandem mass spectrometry) is used to separate and analyse the mix of peptides that go to make up proteins.

One of the recent developments in medicine are antibody drug conjugates (ADC). This involves the coupling of a drug to an antibody that has been designed to target a specific type of cell — a cancer cell. The system allows the drug to be delivered to the inside of the cancer cell, killing the cancer cell and not the healthy surrounding cells. Because of the nature of these products, new columns are required as discussed in this article, New Innovations in UHPLC and multidimensional Workflows for the Characterisation of Bio-Therapeutics.

Do you fancy a week in San Francisco?

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