Smoking 'contributes' to oxidatively induced DNA damage
Smoking cigarettes is a known cause of cancer

HPLC, UHPLC

Smoking 'contributes' to oxidatively induced DNA damage

13 May, 2011

Published over 15 years ago. See the latest and most current information on HPLC, UHPLC.

Liquid chromatography has been used in a study to see whether smoking cessation has an effect on reversing oxidatively induced DNA damage.

The report, taken from Tobacco Induced Diseases, looked at how three DNA lesions reduced after participants had kicked the habit.

A sample of people from a 16-week smoking cessation clinical trial were used, with blood samples taken and leukocyte DNA extracted for the 3 DNA lesions through liquid chromatography tandem mass spectrometry.

Following this, a change in lesions over time was looked at using generalised estimating equations, taking into account gender, age and treatment condition.

"Results from this analysis suggest that cigarette smoking contributes to oxidatively induced DNA damage, and that smoking cessation appears to reduce levels of specific damage markers between 30-50 percent in the short term," the report concluded.

Recently, a smoking ban in public places was introduced in China, affecting more than 300 million people.

Latest News

Explore Our Other Sites

Labmate Online
Mayo Clinic and Thermo Fisher Scientific launch Precure LLC to identify signs of disease before their symptoms appear
Explore more Arrow
Envirotech Online
Connected safety technology company announces CEO appointment and leadership transition
Explore more Arrow
Pollution Solutions Online
Smarter wastewater management helps futureproof distillery operations and protect local watercourses
Explore more Arrow
Petro Online
Improving repeatability in diesel fuel lubricity testing
Explore more Arrow