• Quantitative analysis used in MRSA study
    Scientists have identified the evolution of MRSA clone success.

Electrophoretic Separations

Quantitative analysis used in MRSA study

Sep 30 2011

Scientists have used quantitative analysis processes to determine the genetic relatedness of Western Australian community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) clones within different multilocus sequence type (MLST) clonal clusters.

CA-MRSA is now the predominant strain of MRSA isolated in the state of Western Australia, with the team from Royal Perth Hospital aiming to gain insight into the frequency of S.aureus SCCmec acquisition within a region.

The study, published in BMC Microbiology, found that the CA-MRSA population in Western Australia is genetically diverse and has some 83 unique pulsed-field gel electrophoresis strains, 46 MLSTs of which have been characterised.

It determined that although SCCmec IV and V are the predominant SCCmec elements, SCCmec VIII and several novel and composite SCCmec elements are present.

"Only three clones have successfully adapted to the Western Australian community environment. These data suggest the successful evolution of a CA-MRSA clone may not only depend on the mobility of the SCCmec element but also on other genetic determinants," the report concluded.

Digital Edition

Chromatography Today - Buyers' Guide 2022

October 2023

In This Edition Modern & Practical Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...

View all digital editions

Events

EuCheMS Chemistry Congress

Jul 07 2024 Dublin, Ireland

HPLC 2024

Jul 20 2024 Denver, CO, USA

ICMGP 2024

Jul 21 2024 Cape Town, South Africa

ACS National Meeting - Fall 2024

Aug 18 2024 Denver, CO, USA

View all events