• Quantitative analysis of twins' DNA conducted with electrophoresis

Electrophoretic Separations

Quantitative analysis of twins' DNA conducted with electrophoresis

Dec 10 2010

Inter-Alu polymerase chain reaction (PCR) products have been studied using electrophoresis as part of quantitative analysis of monozygotic twins' genetic polymorphisms.

Writing in BMC Bioinformatics, a team of scientists from Bologna University and the Italian National Research Centers on Aging explain how they used capillary electrophoresis to analyse inter-Alu PCR products for differences theoretically arising due to experimental variability.

Monozygotic twins are "identical" in terms of DNA and are caused by a single fertilised egg dividing to form two embryos.

By comparison, dizygotic twins occur when two different eggs are fertilised and carried to term - and can be either same-sex or boy-girl pairs.

In their study, the scientists found the Haar-Walsh Wavelet Packet Transformation to be a suitable basis for quantitative analysis of twins' DNA as part of an error-reducing process to improve subjective evaluation of samples.

The periodical carries the latest findings of how statistical and computational techniques can be applied to scientific research.

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