• Quantitative analysis of mouse saliva indicates impact of tannins
    The effect of a tannin-rich diet has been studied by Portuguese scientists using quantitative analysis based on electrophoretic separation

Electrophoretic Separations

Quantitative analysis of mouse saliva indicates impact of tannins

Dec 17 2010

Quantitative analysis of mouse saliva has been carried out in order to determine the impact of a tannin-rich diet on the expression of proteins.

The study, carried out by scientists at the Universidade de Evora in Portugal and published in Proteome Science, relates the quantitative analysis of proteins expressed in mice with control and tannin-enriched diets.

According to the researchers, "this proteomic analysis provides evidence that other salivary polypeptides, in addition to tannin-precipitating proteins, are affected by tannin ingestion".

In all, 57 protein spots were selected from electrophoretic gels belonging to the control group for a total of 21 unique proteins identified.

A number of these were differently expressed in mice with tannin-enriched diets, while the results hinted proline-rich proteins may form soluble complexes in the presence of tannins.

Proteome Science says it will consider research in a number of fields, including mass spectrometry, protein arrays, structural biology and bioinformatics.

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