• Quantitative analysis of chicken proteins yields potential for adipogenesis
    Femoral adipogenesis in chickens has been studied with quantitative analysis of proteins

Electrophoretic Separations

Quantitative analysis of chicken proteins yields potential for adipogenesis

Sep 15 2010

Adipogenesis - the formation of fat cells - in chicken femurs has been investigated using quantitative analysis of how proteins are expressed in different test subjects.

Writing in Proteome Science, researchers at Taipei Medical University explain how they undertook quantitative analysis of the proteins present in healthy chickens and in those with adipogenesis induced by steroids.

In all, 13 proteins were expressed differently between the two groups, with downregulation to a factor of three or more in nine protein spots.

The analysis was carried out after 19 weeks of treatment with methylprednisolone, a steroid used to trigger adipogenesis in the chickens' femoral bone marrow.

With significant protein differences between healthy and adipogenetic subjects, the scientists suggest that proteomic profiling could be useful for detecting how expression varies between individuals.

In turn, they argue that their findings could develop into a means of testing for potential onset of steroid-induced femoral osteonecrosis.

Digital Edition

Chromatography Today - Buyers' Guide 2022

October 2023

In This Edition Modern & Practical Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...

View all digital editions

Events

NGVS 2024

May 23 2024 Beijing, China

Analiza

May 28 2024 Tel Aviv, Israel

HTC-18

May 28 2024 Leuven, Belgium

PREP 2024

May 28 2024 Philadelphia, PA, USA

CISILE 2024

May 29 2024 Beijing, China

View all events