• Measuring absolute density in active species could lead to better treatments

Electrophoretic Separations

Measuring absolute density in active species could lead to better treatments

Nov 21 2012

Considerable advances have been made in measuring the density of active species utilised in medical applications of plasma physics which may improve the precision of treatment.

For the first time ever, the absolute density of active substances, named radicals, which are found in a state of matter known as plasma, has been measured, according to an international group of researchers and scientists working at the Plasma Technology research unit at Ghent University in Belgium.

This discovery might have significant implications for medicine, such as inducing a targeted antiseptic effect in vivo without affecting nearby tissues, or simulating tissue regeneration.

In order to detect and estimate the density of radicals in plasma, the team of scientists used laser fluorescence spectroscopy.

Plasma is made of charged species which are active molecules such as atoms and radicals.

Being one of the most vital reactive species in plasma science because of their high level of oxidation, scientists opted to focus on OH radicals.

Damaging components in the human body or in nature, such as methane, volatile organic compounds and carbon monoxide are shattered by the chemical reactions from OH radicals.

Due to the problems with registering and analysing the fluorescence signal, laser-induced fluorescent capacity to gauge the absolute density of radicals has been very restricted, up until this new discovery.

Inclusive of energy transfer stemming from the radicals' vibrations, the scientists have supplied a simplified model in this study.

It can be utilised to examine the laser fluorescence spectroscopy signal at the usual atmospheric pressure.

The scientists can then confirm experimentally whether their model is valid, with a plasma jet made of water molecules combined with argon gas.

"The calculation of one-dimensional line-averaged OH density made in this paper could also be extended to a two-dimensional spatial resolution of the OH radicals in future work," stated the research article.

The study will be published in The European Physical Journal D.

Posted by Ben Evans

Digital Edition

Chromatography Today - Buyers' Guide 2022

October 2023

In This Edition Modern & Practical Applications - Accelerating ADC Development with Mass Spectrometry - Implementing High-Resolution Ion Mobility into Peptide Mapping Workflows Chromatogr...

View all digital editions


ACS National Meeting - Fall 2024

Aug 18 2024 Denver, CO, USA

JASIS 2024

Sep 04 2024 Chiba, Tokyo, Japan

BMSS-BSPR Super Meeting 2024

Sep 04 2024 University of Warwick, Coventry, UK

Mass Spectrometry 2024

Sep 10 2024 Rockville, MD, USA

Plastics Recycling World Expo Europe

Sep 11 2024 Brussels, Belgium

View all events