CBS 'dramatically improves' workflow and productivity

An innovative user-friendly compound-based scanning software system significantly simplifies multi-residue analysis and leads to an increase in workflow and productivity, according to a recent article published in Chromatography Techniques.

Gas Chromatography (GC), coupled to a triple quadrupole Mass Spectrometer (GC-MS/MS-QqQ) operated in MRM mode is increasingly the preferred technique for multi-residue analysis in complex matrix samples by analytical laboratories. However, the process can be quite a complex one for those that aren't expertly trained in mass spectrometry.

In order to simplify the method, analytical research manufacturer Bruker have introduced new Compound Based Scanning (CBS) software in the proprietary SCIONTM TQ system, which makes the system more user-friendly.

The new work flow focuses on compounds and not each MRM, which means the MRM transition of an analyte does not need to be known by the user. The software has a factory-installed read-only compound library that contains over 2,500 MRM transitions for more than 900 common contaminants, which allows it to auto-fill information. Other advantages are that CBS can set up a method and manage the duty cycle during analysis and data acquisition, as well as being able to link compounds to retention time, primary and secondary MRM transitions, and collision energy.

Posted by Neil Clark