• High Throughput Requires Low Downtime

HPLC, UHPLC

High Throughput Requires Low Downtime

Nov 19 2013

The importance of a reliable supply of nitrogen is often overlooked. To maximise profitability the pharmaceutical industry puts high demands on the instrumentation used. An integral part of many processes is the LC-MS and peripheral equipment. If any part of the system requires downtime, planned or unplanned, it affects profitability.

The cost of the raw materials and the cost of the LC-MS dwarf the cost of a nitrogen generator, yet it is this that can cause most problems if not chosen wisely.

Nitrogen generators which incorporate a compressor in the same box are asking for trouble. This type of system runs the risks of vibration, overheating and delivering moisture to the membrane. All three of which will result in increased downtime, higher costs and replacement parts. A service contract is a must for such systems.

Nitrogen generator systems from cmc Instruments do not run this risk. In addition the membrane is of higher quality and lower ratio than the norm in these instruments, ensuring a longer lifetime. Four filters further ensure that only clean, dry air is presented to the membrane. Annual maintenance involves a filter change and can be performed by the user in fifteen minutes. No service contract is needed.

cmc Instruments have been designing and manufacturing all their gas generators in Germany, a country synonymous with quality and reliability, for the last 20 years. In that time they have become market leader and can only recall changing a membrane on three nitrogen generators out of the thousands supplied. Isn’t that reassuring?

The belief at cmc Instruments is that it is not how much you pay on day one that matters. It is the years of service, the cost of ownership and lowest possible downtime that are most important. Customers tend to agree.

cmc Instruments manufacture a wide range of gas generators including nitrogen generators for LC-MS applications, high purity PSA nitrogen generators, hydrogen generators for GC applications, zero air generators, purge gas generators and TOC gas generators – all to the same high standards.


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