UHPLC-MS reveals steamed P notoginseng may combat liver cancer
Steamed P notoginseng has greater anti-cancer properties, UHPLC-MS analysis reveals

HPLC, UHPLC

UHPLC-MS reveals steamed P notoginseng may combat liver cancer

26 Jan, 2011

Published over 15 years ago. See the latest and most current information on HPLC, UHPLC.

Liver cancer could be combated using steamed Panax notoginseng, according to ultra high performance liquid chromatography and mass spectrometry (UHPLC-MS) analysis of the root.

Powdered, uncooked P notoginseng roots were steamed for a variety of different periods of time by a team of scientists from the National University of Singapore, Republic Polytechnic and Singapore Institute for Clinical Sciences.

Their findings are published in Chinese Medicine, a periodical from the International Society for Chinese Medicine which addresses all aspects of the discipline.

Using UHPLC-MS to analyse the chemical profiles of the roots after steaming, the scientists were looking for anti-proliferative effects on liver cancer cells.

Intriguingly, they found the chemical changes associated with up to 24 hours of steaming enhanced the anti-cancer effects of the roots.

"Steaming changed chromatographic and pharmacological profiles of P notoginseng, causing differences in activities such as inhibition of cancer growth," the researchers report in their study.

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