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GC, MDGC, GC-MS

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    Leaks in a GC System

    We have had enquiries from our readers about leaks in their GC instrumentation.  This article will look at some of the ways of identifying these leaks in a gas chromatography system and also highlight some of the issues that can be caused by having a leaky system. Leaks of the carri...

    GC, MDGC, GC-MS

    February 2014

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    Improved GC Columns for the Petroleu...

    Petroleum analysis makes extensive use of specialised columns for gas chromatography, with continuous expectations from the industry for better columns that improve analytical performance and chromatographic efficiency. In this article we discuss two new developments in GC column techno...

    GC, MDGC, GC-MS

    February 2014

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    Why is my Method Not Robust?

    With the first edition of Chromatography Today Helpdesk, it was thought one of the most common issues, namely of non-robust methods, should be addressed. Why do assays keep falling over and what can be done to make them stable is a question that keeps many scientists and lab managers aw...

    GC, MDGC, GC-MS

    June 2013

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    The Need for Speed Applying Triple Qu...

    Gas chromatography-mass spectrometry (GCMS) is a technique widely used in this sector, however with analysis runs that may take several hours to complete, and with repeat testing often needed, the market is inevitably calling for increased speed from both preparation methods and instrum...

    GC, MDGC, GC-MS

    March 2013

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    Headspace Gas Chromatography as a Gr...

    Headspace-Gas Chromatography (HS-GC) has been evaluated as a green alternative for the elimination, or at least the large reduction, of solvents in analytical determinations. The direct use of HS-GC and the pre-concentration of analytes in the HS vial offer fast, safe, sensitive and sel...

    GC, MDGC, GC-MS

    December 2012

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    Intelligent use of Relative Response...

    Quantitative analysis is required in pharmaceutical R&D to measure the quality of materials used in active pharmaceutical ingredient (API) manufacture, and to monitor the composition of reactions over time.  Reagents and matrix typically contain organic carbon, are often volatile and c...

    GC, MDGC, GC-MS

    May 2012


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