Understanding HILIC separation and improving your results
Jul 28 2020 Read 391 Times
Do you regularly work with HILIC columns?
Do you have a new project that requires you to try a HILIC separation?
You probably know that hydrophilic interaction chromatography (HILIC) is very different from reversed phase chromatography and the development of a robust and reproducible HILIC method can be a challenging process. Because HILIC is less well understood than other chromatographic methods the success of a method is often perceived to be predestined by the physicochemical properties of the analytes. This is something you can’t change, but can you use it to your benefit?
YMC have prepared a review highlighting influences on the separation mechanisms in HILIC mode as a helpful tool for method development and troubleshooting.
Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.
In This Edition Articles Fundamental Aspects - Separation of the 4 Enantiomers of the Fungicide Spiroxamine by LC-MS/MS - Optimising the Chiral Separation of the Pesticide Diniconazole...
View all digital editions
Sep 08 2020 Sheffield, UK
Sep 14 2020 Virtual Symposium
Sep 21 2020 Budapest, Hungary
Sep 27 2020 Saint-Malo, France
Sep 28 2020 Bethesda, MD, USA