Liquid chromatography reveals relationship of vitamin C in dialysis patients
May 09 2011 Comments 0
The study was published in BMC Nephrology and the cross-sectional assessment saw scientists scrutinise 284 dialysis patients, including 167 on continuous ambulatory peritoneal dialysis (CAPD) and 117 using maintenance hemodialysis (MHD).
Using high-performance liquid chromatography, the team discovered that vitamin C deficiency was present in just under a third of those studied and insufficiency in almost 31 per cent.
They also found that plasma vitamin C level was inversely associated with log10hsCRP and positively linked with prealbumin levels.
"The investigation indicates that vitamin C deficiency is common in both MHD patients and CAPD patients," the team stated.
It suggested that while the findings suggest vitamin C deficiency can increase inflammatory status in dialysis patients, further studies are needed to determine if this can be improved with the use of vitamin C supplements.
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