Chiral

  • New addition to YMC's immobilised chiral column portfolio
    The new immobilised CHIRAL ART Cellulose-SZ extends your options in chiral HPLC and SFC.

New addition to YMC's immobilised chiral column portfolio

Nov 24 2020

YMC offers several CHIRAL ART polysaccharide columns, which are either immobilised or coated, for the separation of different types of chiral compounds. Currently there are four immobilised and two coated chiral selectors available – and there is more to come!

New and innovative immobilised phase!

At Analytica Virtual 2020, YMC announced the extension of its chiral portfolio with the introduction of their new immobilised CHIRAL ART phase! The new CHIRAL ART Cellulose-SZ phase offers a new chiral selector. The innovative immobilised chiral selector is cellulose tris(3-chloro-4-methylphenylcarbamate). To date this chiral stationary phase (CSP) has only been available as a coated type from traditional suppliers (e.g. OZ or Cellulose-2).

More options and flexibility

This new immobilised version provides unrestricted use in NP-, RP- or SFC mode and offers a complementary selectivity of other CHIRAL ART phases. Notably a broader range of different sample solvents is possible. Many substances are inadequately soluble in solvents used for NP mode and solvents such as THF, DMF, DMSO or dichloromethane have to be removed, even in trace concentrations when using coated phases. In contrast, the immobilised CHIRAL ART Cellulose-SZ phase offers full compatibility with such solvents and therefore much more flexibility.

Robust analyses

Like YMC’s other immobilised phases, CHIRAL ART Amylose-SA, Cellulose-SB, Cellulose-SC and Cellulose-SJ, CHIRAL ART Cellulose-SZ ensures robust analyses. This immobilised chiral portfolio is complemented by the phases with the highest hit rates, CHIRAL ART Amylose-C and Amylose-C Neo respectively which provide even higher resolutions and loadabilities as well as the classic Cellulose-C. These phases are coated CSPs that can only be used in NP and especially SFC modes.

Particle sizes according to the application

All CSPs are available with 3 and 5 µm for analytical and (semi)preparative applications as well as with 10 and 20 µm for process scale. All phases have the same YMC silica base and the YMC-developed coating or bonding technology in common, while their chiral selectivities are quite different. CHIRAL ART columns are very long-lasting. They are the ideal choice for purifications in semipreparative or preparative scale due to their high stability. The pressure stable YMC-Actus (semi)preparative column hardware allows high flow rates which results in fast runs.

Reliable QC

As with each quality control, the foundation of a chiral QC is reliable lot-to-lot reproducibility. Of course, the new CHIRAL ART Cellulose-SZ columns offer YMC’s well-known excellent lot-to-lot reproducibility together with an outstanding stability and lifetime. These properties make the new columns first choice for your QC!


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