• Three triple quads achieve a new global standard in mass spectrometry

HPLC, UHPLC

Three triple quads achieve a new global standard in mass spectrometry

Apr 23 2014

Three triple quadrupole mass spectrometers GCMS-TQ8030, LCMS-8040 and LCMS-8050 complete Shimadzu’s UFMS series consisting of seven powerful systems. The UFMS product family provides higher sensitivity, greater excellence in data quality, increased analytical throughput and a wider range of applications.

The LCMS-8040 and LCMS-8050 expand the analytical range of Shimadzu's LC-MS/MS lineup while the GCMS-TQ8030 achieves new levels of speed and sensitivity in GCMS analysis.

GCMS-TQ8030 - ultra-fast analysis meets sensitivity and accuracy

The GCMS-TQ8030 achieves the highest sensitivity in its class for multiple reaction monitoring (MRM) measurements based on UFsweeper® technology. Superior mass spectra and sensitivity at high scan speeds of up to 20,000 masses/sec is achieved using Advanced Scanning Speed Protocol (ASSP™).

The GCMS-TQ8030’s ecology mode reduces carbon dioxide emissions through a reduction of power consumption in analysis standby mode of 36% while also decreasing the consumption of carrier gas.

LCMS-8040 - Expanded range of ultra-fast, high-sensitivity applications

The system combines newly improved ion optics and collision cell technology with proprietary ultrafast technologies. This significantly expands the application range and ensures high-sensitivity, high-throughput analysis at lower levels of detection. A five-fold increase in sensitivity (reserpine, S/N ratio) has been achieved when compared with the LCMS-8030 model.

The LCMS-8040 is the world’s fastest LCMS/MS tandem mass spectrometer and provides multiple reaction monitoring (MRM) transition speeds of up to 555 MRMs per second. This is based on UFsweeper® II collision cell technology that maintains sensitivity and suppresses cross-talk, even for high-speed or simultaneous multi-component analyses.

LCMS-8050 - Trace level quantitation of multiple compounds

Shimadzu’s LCMS-8050 triple quadrupole LC-MS/MS meets the growing demand for trace-level quantitation in clinical research and other markets. It incorporates proprietary ultrafast technologies as well as a newly developed ion source and collision cell technology. As the flagship model of Shimadzu’s UFMS (Ultra-Fast Mass Spectrometry) product line, the LCMS-8050 features high sensitivity, high data quality and the world’s fastest data acquisition rates.

Delivering attogram-level (10-18 grams) sensitivity and possessing unsurpassed ruggedness, the LCMS-8050 achieves its improved sensitivity through two important technologies:

  • Newly designed Heated ESI source improves desolvation and enhances ionization efficiency with the addition of a heated gas used in combination with the nebulizer gas
  • UFsweeper®III collision cell enhances CID efficiency by optimizing the collision cell pressure.

The world’s fastest data acquisition rates

The newly engineered high voltage power supply enables a maximum scan rate of 30,000 u/sec and a 5 msec polarity switching time, making the LCMS-8050 combined with Nexera UHPLC the ideal platform for laboratory productivity. It is now possible to include 1,000 events with up to 32 channels per event for a maximum of 32,000 MRMs per analysis.

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