Revised USP Chapter <841> enables 50% OOS reduction!


The two largest sources of laboratory errors come from sample processing (30%) and human operation (19%). In addition, the amount of laboratory time spent processing samples is estimated to be greater than 60%.

The revised USP Chapter <841> Specific Gravity posted in February 2013 states that samples can now be prepared by weight, as well as by the historical method of volume.

Gravimetric liquid dispensing compensates for any under or overshoot of the sample weight to produce extremely accurate, confirmed concentrations. Stock and final solutions are prepared in fewer steps and with minimal human interaction.

Implementing a gravimetric sample preparation system reduces laboratory errors and Out-of-Specification (OOS) incidents by up to 50%, while increasing laboratory efficiency.

Download the white paper on gravimetric sample preparation and find out how the revision of USP Chapter <841> could benefit you.

Make the shift - choose the right solution
To help you move from volumetric to gravimetric sample preparation, discover the range of solutions available from METTLER TOLEDO.

The Quantos product portfolio offers accurate, precise dispensing at a touch of a button. The range of options includes enhanced analytical balances, solutions for medium throughput dispensing and automated sample preparation systems ideal for numerous sample runs, Find out more.

For further information or to book a product demonstration, email

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