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The power of new analytics flaunted in l...

A complete LC/MS/MS laboratory-on-wheels will tour America next month flaunting the power of new-generation analytic too...

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MSE method provides qualitative informat...

Methylation specific electrophoresis (MSE) has been found to be an effective qualitative method for providing informatio...

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Post-transitional modification found in...

Two-dimensional difference gel electrophoresis and immunoblotting have been used to compare excretory-secretory antigens...

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Chemists create 'green' method for devel...

US researchers say they have come up with an environmentally-friendly way of developing medicines. It is thought the ne...

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Comprehensive Two-Dimensional Gas Chroma...

Zoex Corporation's GC x GC software is making two-dimensional gas chromatography an accessible tool for routine lab anal...

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Mechanisms driving fat accumulation in D...

Researchers using gas chromatography and mass spectrometry have found differences in desatrase activity among sufferers...

Feb 06 2012 04:28 PMRead more

Bioanalytical

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Preparation and LC/MS Analysis of Oligon...

Due to their association with other biomolecules as well as their unique chemical properties, oligonucleotide therapeutics present unique challenges i...

Bioanalytical

March 2011
In-silico prediction of retention times...

It is established that for electrospray LC-MS(/MS) assays, co-eluting phospholipids may cause ion suppression which can lead to method inconsistency a...

Bioanalytical

June 2010
The Development of Dry Plasma Spot Analy...

Introduction Anyone reviewing the hottest buzzwords in bioanalysis over the last few years could not escape the phrase ’Dry Blood Spot’ or DBS. The a...

Bioanalytical

June 2010
The Changing Face of Bioanalysis

This is a pharmaceutical industry perspectiv of the way bioanalytical technologies are changing in response to the changing types of molecules under d...

Bioanalytical

June 2009
Drug Bioanalysis by LC-MS: some pragmati...

The use of atmospheric pressure ionisation (API) LC-MS/MS has been very successful in drug bioanalysis. Despite this, many challenges, such as those p...

Bioanalytical

June 2009

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The Role of Chromatography in Bioanalyti...

The accurate determination of the concentration of a drug candidate and it’s resulting metabolites in biological fluids plays an essential in the drug discovery, preclinical and clinical development programs. The drug concentration values determined are used to calculate the pharmacokineti...

Bioanalytical

June 2009
Development of an automated method for m...

Two major problems in biotherapeutics are aggregation of and the presence of variants of active pharmaceutical ingredients. These product-related substances can have different efficacy than the main product and may cause serious side effects, for example, anti-drug-antibody formation. Prot...

Bioanalytical

June 2009
Turbulent Flow Chromatography: an Evolvi...

Bioanalysis has evolved considerably over the last ten years with the rapid implementation of three key technology levers: robotics for automated sample extraction, fast liquid chromatography coupled to mass spectrometry for high throughput trace analysis and finally Laboratory Information...

Bioanalytical

September 2009

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